Introducing SPLENDID™

A culture-free, direct-from-blood platform for ultra-rapid pathogen identification (ID) and phenotypic antimicrobial susceptibility testing (AST)

SPLENDID™ is engineered to expedite the diagnosis of bloodstream infections to empower clinicians with timely and actionable results to inform early treatment decisions.



Clinical blood samples (5-10 mL) are processed in minutes, isolating pathogens for ID and AST without waiting for multi-day blood cultures.

BLASTID Splendid Platform

Drive Clinical Action from the Start.

Isolation & Detection
< 30 min

Compatible with downstream analytical & clinical workflows.

Isolate polymicrobial samples.

Illustration of a device with sections labeled 'Fungal Trap' and 'Bacterial Trap,' showing flow direction downward and plus symbols on the side.

Classification / Species ID
< 1 hour

Super-resolution microscopy with real-time quantification.

ID with AI-powered algorithms.

Bacterial species identification method by BLASTID

Phenotypic AST
1- 3 hours

Single-cell analysis using live whole pathogens.

Determine targeted treatment.

Antibiotic suseptibility test next generation culture free phenotypic analysis AI

Current diagnostic workflows for pathogen ID and AST rely on multi-day blood cultures.

The 2-5 day delay leads to worse patient outcomes and increased healthcare costs

1-in-4 Positive Blood Cultures Takes >24 Hours

Graph showing bottle count distribution over hours with cumulative percentages for five days, with days labeled at the top and total samples in parentheses.

SOURCE: Ransom EM, et al., J Clin Microbiol (2021)

Pathogens Detected in Blood Culture

Gram-negative bacilli 62.0% Gram-positive cocci 35.4% Yeast / fungi 1.5% Gram-positive bacilli 1.0% Gram-negative cocci 0.1%

SOURCE: Opota et al., Clin Microbiol Infect. (2015)

Gram-negative bacteria Gram-positive bacteria Yeast / fungi 24 h clinical threshold E. coli S. aureus K. pneumoniae A. baumannii Enterobacter spp. Enterococcus spp. P. aeruginosa Candida spp. C. glabrata 0 h 12 h 24 h 36 h 48 h 60 h 72 h Time to positivity (hours)

This delay ripples across the healthcare system

  • Patients face increased risk of adverse outcomes and mortality

  • Laboratories and hospitals absorb mounting operational and economic costs

  • Addressing this diagnostic gap is both a clinical imperative and a significant opportunity to improve healthcare system efficiency and quality

SOURCE: Lambregts, et al., PLoS One (2019)

>30 Million

Blood cultures performed in US

>20%

Proportion of patients who receive inappropriate treatment for BSI

15% - 30%

Blood culture contamination rate (costly false positives)

2 - 3
Weeks

Culture to rule out fungal infection

SOURCES: Katri et al. The Lancet (2021); Rangel-Frausto, et al. JAMA (1995); Banerjee et. al, JAMA (2026)

BSI: Bloodstream Infections

SPLENDID™ eliminates blood culture, expediting ID and AST results to inform initial treatment decisions.

See how SPLENDID™ exposes pathogens that hide between billions of other host cells

Conventional and rapid workflows require positive blood culture to even start ID or AST testing.

SPLENDID delivers results when it matters most.

Isolation & Detection

< 30 Minutes

Pathogen isolation and enrichment to detect any bacterial or fungal cells within whole blood

Classification & Species ID

< 1 Hour

Classification and pathogen identification through AI-powered algorithms

Phenotypic
AST

1 - 3 Hours

Phenotypic AST informs precise, targeted treatment for a patient’s infection

Results that Influence Initial Treatments.

Answers before empiric therapy has a chance to fail.

Positive blood culture Gram stain and ID AST SPLENDID-AST Rapid ID and AST Conventional 1-3 h Positive blood culture (PBC) AST Positive blood culture (PBC) Gram stain and identification (ID) Susceptibility testing (AST) 0 8 16 24 32 40 48 56 Time from blood draw (hours) ~2 days faster vs. conventional ID/AST

SPLENDID™ delivers fast and actionable clinical intelligence.

  • Integrated ID & AST

  • Phenotypic AST

  • Live whole cells

  • Inform targeted treatment

Capability SPLENDID-AST Direct from Blood 5-10 mL Identification < 1 hour Phenotypic AST 1-3 hours Live-Cell Assay Non-destructive Polymicrobial Single-cell Analysis Point-of-Care Benchtop Low Limit of Detection 1 to 2 CFU/mL

A Benchtop Platform Built for Ease of Use.

SPLENDID Platform Dimensions Benchtop Platfrom to fit in your lab

The system pairs single-use cartridges with integrated software to deliver clinically actionable results

Load the blood vacutainer and start the run. The instrument automates sample processing, image capture, and AI-powered analysis.

  • Sample: 5-10 mL whole blood

  • Footprint: Compact benchtop instrument

  • Consumables: Single-use integrated cartridges

  • Workflow: Minimal hands-on time

Join us on the journey to redefine bloodstream diagnostics.

Collaborate with BLASTID.

BLASTID is actively engaged with hospital systems, clinical laboratories, and key stakeholders to bring culture-free, direct-from-blood diagnostics into routine practice.

Join us on the journey to unlock massive patient impact and commercial success.