Sepsis Diagnostics Platform.jpeg

SEE THE ONE  

IN A BILLION.

Single cell diagnostics aiming to expedite care when it matters.

From whole blood to antibiotic susceptibility test (AST) in hours, expediting time to optimal treatment to save patients’ lives.

» EXPLORE THE PLATFORM

» SEE THE BREAKTHROUGHS

Sepsis Blood Diagnostic

We develop direct-from-blood diagnostic solutions leveraging breakthroughs in live-cell imaging and AI-powered analysis.

Detect as few as 1 to 100 pathogens in a single 10 mL blood sample

SPLENDID™ exposes the unseen in minutes to drive clinical action.

Detect 1 pathogen among 50 billion host cells.

See what’s hiding in a 10 mL blood sample

FROM BLOOD DRAW TO DIAGNOSIS IN MINUTES

SPLENDID™ Isolates & Characterizes Living Cells.

Culture-free, ultra-rapid platform for single-cell isolation and phenotypic characterization.

  • Empower clinicians with timely and accurate diagnostics

  • Automated sample handling directly from vacutainer tube

  • Life-saving results in the first hours of treatment

  • Isolate pathogens directly from patient samples within minutes

  • Label-free methods utilizing novel super-resolution, time-lapse imaging of captured cells

  • AI-powered image analysis with proprietary classification and characterization algorithms

SPLENDID™ is under development and not FDA approved for clinical diagnostics. 

SPLENDID™ collapses a 2-5 day process into 1-3 hours

Positive blood culture Gram stain and ID AST SPLENDID-AST Rapid ID and AST Conventional 1-3 h Positive blood culture (PBC) AST Positive blood culture (PBC) Gram stain and identification (ID) Susceptibility testing (AST) 0 8 16 24 32 40 48 56 Time from blood draw (hours) ~2-5 days faster vs. conventional ID/AST

Patients can’t afford to wait.

BY THE NUMBERS: SEPSIS STATISTICS IN THE U.S. (2021)

>30 M

Blood Cultures

2.5 M

Patients Diagnosed

>350 K

Patient
Deaths

>$100 B

Healthcare
Costs

SOURCES: Patel et al., BMJ Open Qual. (2025); Global Sepsis Alliance; Sepsis Alliance; Buchman et al., Crit. Care Med (2020)

EMPIRIC Traditional 0 h Blood culture initiated 1-3 h Empiric treatment broad-spectrum Wait and see clinical response 3-24 h Gram stain rapid ID and AST 24-48 h Species ID and conventional AST >72 h 0 h 3 h 24 h 48 h 72 h Time since blood draw SPLENDID* Rapid diagnostics 0 h Blood draw initiated 1-3 h Detection, species ID and AST complete ~2-5 days faster to actionable result

WHY ULTRA-FAST RESULTS MATTER

Critically ill patients can’t wait days for results, and doctors can’t wait to make treatment decisions.

Every hour appropriate treatment is delayed increases a patient’s risk of developing complications and reduces the chance of survival.

Empowering Clinicians with Actionable Results

  • Laboratory equipment with a white enclosure, a computer screen, and a device with a turbine-like component.

    The Platform

    Explore how SPLENDID™ delivers clinically actionable results in minutes. 

  • Microscopic image of a cell division process with a line of small round cells in the center and two large metallic structures on each side.

    The Breakthroughs

    The innovations powering SPLENDID™ to see the rare pathogen in blood samples. 

OUR MISSION

Provide clinically actionable results to personalize patient care in minutes instead of days.

Sepsis takes a life every 2.8 seconds globally, yet doctors must wait days for definitive answers.  

We close the gap between sample and answer to guide patient care, pioneering diagnostics that are faster, smarter, and clinically actionable.

BLASTID is led by diagnostic veterans, esteemed clinicians, & world-renowned scientists. We are a driven team united to solve a problem that kills >20 million people every year.

»LEARN MORE ABOUT OUR MISSION

SOURCE: Global Sepsis Alliance 

  • Launched through a global vision to defeat Antimicrobial Resistance (AMR) through transformative solutions.

    LEARN MORE

  • The operators, engineers, and scientists building SPLENDID™, and the pioneering advisors supporting BLASTID. 

    MEET US

  • If you want to transform diagnostics, connect with us.

    SEE OPEN POSITIONS

BLASTID spun-out of Harvard to defeat antimicrobial resistance through transformative clinical solutions with support from the ARPA-H DARTS program.

Our Partners & Collaborators

Ready to see one in a billion?

Partner with us today.

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Headquarters:

135 William T. Morrissey Blvd
Suite P101
Boston, MA 02125

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